Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19430398 | 0.89 | S1PR1 (0.45) | S1PR1SPHK2 | |
| SCHEMBL19430707 | 0.88 | SPHK2 (0.53) | S1PR1SPHK2 | |
| SCHEMBL19430718 | 0.87 | S1PR1 (0.43) | S1PR1SPHK2 | |
| SCHEMBL19430701 | 0.82 | SPHK2 (0.49) | S1PR1SPHK2 | |
| SCHEMBL22280466 | 0.81 | SPHK2 (0.49) | S1PR1SPHK2 | |
| SCHEMBL19430878 | 0.81 | S1PR1 (0.50) | S1PR1SPHK2 | |
| SCHEMBL17666215 | 0.80 | SPHK2 (0.42) | S1PR1SPHK2 | |
| SCHEMBL19430602 | 0.79 | SPHK2 (0.46) | S1PR1SPHK2 | |
| SCHEMBL17666209 | 0.78 | NPSR1 (0.39) | S1PR1SPHK2 | |
| SCHEMBL19430684 | 0.78 | SPHK2 (0.51) | S1PR1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017172989-A1 | SPHINGOSINE KINASE INHIBITOR AMIDOXIME PRODRUGS | THORPE STEVEN BRANDON (US) | 2017-10-05 | — | — | WO | disclosed |