Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.67 |
| ▸ | ACE | P12821 | 8/20 | 0.58 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.57 |
| ▸ | NPY4R | P50391 | 1/20 | 0.57 |
| ▸ | MME | P08473 | 6/20 | 0.55 |
| ▸ | CPA1 | P15085 | 2/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.55 |
| ▸ | IL1RN | P18510 | 2/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520794 | 0.88 | FOLH1 (0.67) | FOLH1ACENPY1RNPY2RNPY4R | |
| SCHEMBL19432688 | 0.88 | NPY4R (0.60) | FOLH1ACENPY1RNPY2RNPY4R | |
| SCHEMBL30845374 | 0.86 | FOLH1 (0.68) | FOLH1ACENPY1RNPY2RNPY4R | |
| SCHEMBL29531459 | 0.86 | FOLH1 (0.68) | FOLH1ACENPY1RNPY2RNPY4R | |
| SCHEMBL29530884 | 0.86 | FOLH1 (0.68) | FOLH1ACENPY1RNPY2RNPY4R | |
| SCHEMBL29350874 | 0.86 | FOLH1 (0.68) | FOLH1ACENPY1RNPY2RNPY4R | |
| SCHEMBL20931095 | 0.86 | FOLH1 (0.61) | FOLH1ACENPY1RNPY2RNPY4R | |
| SCHEMBL22498360 | 0.86 | FOLH1 (0.71) | FOLH1ACENPY1RNPY2RNPY4R | |
| SCHEMBL30845367 | 0.86 | FOLH1 (0.71) | FOLH1ACENPY1RNPY2RNPY4R | |
| SCHEMBL30423308 | 0.86 | FOLH1 (0.71) | FOLH1ACENPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017173347-A1 | PAR2 MIMETIC PEPTIDES AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2017-10-05 | — | — | WO | disclosed |