SCHEMBL20931095

SCHEMBL20931095

CC(C)CC(NC(=O)C(CN)C(C)(C)C)C(=O)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.61
▸ ACE P12821 9/20 0.54
▸ NPY1R P25929 1/20 0.54
▸ NPY2R P49146 1/20 0.54
▸ NPY4R P50391 1/20 0.54
▸ MME P08473 6/20 0.51
▸ CPA1 P15085 2/20 0.51
▸ ACE2 Q9BYF1 2/20 0.51
▸ IL1RN P18510 2/20 0.49
▸ ERAP2 Q6P179 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20931094 0.89 NPY4R (0.57) FOLH1ACENPY1RNPY2RNPY4R
SCHEMBL19432689 0.86 FOLH1 (0.67) FOLH1ACENPY1RNPY2RNPY4R
SCHEMBL10520794 0.84 FOLH1 (0.67) FOLH1ACENPY1RNPY2RNPY4R
SCHEMBL32679640 0.84 FOLH1 (0.67) FOLH1ACENPY1RNPY2RNPY4R
SCHEMBL30797998 0.83 FOLH1 (0.65) FOLH1ACENPY1RNPY2RNPY4R
SCHEMBL30845374 0.82 FOLH1 (0.68) FOLH1ACENPY1RNPY2RNPY4R
SCHEMBL29530884 0.82 FOLH1 (0.68) FOLH1ACENPY1RNPY2RNPY4R
SCHEMBL29350874 0.82 FOLH1 (0.68) FOLH1ACENPY1RNPY2RNPY4R
SCHEMBL29531459 0.82 FOLH1 (0.68) FOLH1ACENPY1RNPY2RNPY4R
SCHEMBL22498360 0.82 FOLH1 (0.71) FOLH1ACENPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11351264-B2 PAR2 mimetic peptides and uses thereof ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2022-06-07 — — US disclosed
US-20190117785-A1 PAR2 MIMETIC PEPTIDES AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2019-04-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11351264-B2 PAR2 mimetic peptides and uses thereof F2RL1, F2R, F2RL3 FOLH1 625/4885ACE 710/4885NPY1R 296/4885
US-20190117785-A1 PAR2 MIMETIC PEPTIDES AND USES THEREOF F2RL1, F2R, F2RL3 FOLH1 625/4885ACE 710/4885NPY1R 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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