SCHEMBL1943651

SCHEMBL1943651

CCCC(=O)O[C@]1(C(=O)CO)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C

nearest known ligand 0.92

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 13/20 0.92
▸ PGR P06401 4/20 0.92
▸ CYP3A4 P08684 4/20 0.92
▸ USP2 O75604 3/20 0.92
▸ MEN1 O00255 1/20 0.92
▸ KMT2A Q03164 1/20 0.92
▸ MMP1 P03956 10/20 0.80
▸ LMNA P02545 2/20 0.76
▸ NR1I2 O75469 2/20 0.76
▸ MAPT P10636 2/20 0.76
▸ MLNR O43193 1/20 0.76
▸ ABCB11 O95342 1/20 0.76
▸ CYP3A5 P20815 1/20 0.76
▸ PPARG P37231 1/20 0.76
▸ SMN1; SMN2 Q16637 1/20 0.76
▸ NPSR1 Q6W5P4 1/20 0.76
▸ CYP2D6 P10635 1/20 0.76
▸ CYP2C9 P11712 1/20 0.76
▸ ADORA3 P0DMS8 1/20 0.75
▸ DRD2 P14416 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11878162 1.00 NR3C1 (0.92) NR3C1PGRCYP3A4USP2MEN1
SCHEMBL11858145 1.00 NR3C1 (0.92) NR3C1PGRCYP3A4USP2MEN1
SCHEMBL11878158 1.00 NR3C1 (0.92) NR3C1PGRCYP3A4USP2MEN1
SCHEMBL11852760 1.00 NR3C1 (0.92) NR3C1PGRCYP3A4USP2MEN1
SCHEMBL5538535 1.00 NR3C1 (0.92) NR3C1PGRCYP3A4USP2MEN1
SCHEMBL11852753 1.00 NR3C1 (0.92) NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL7564753 0.96 NR3C1 (1.00) NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL14339612 0.96 NR3C1 (1.00) NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL9768470 0.96 NR3C1 (1.00) NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL14339607 0.96 NR3C1 (1.00) NR3C1PGRCYP3A4USP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113820416-A Method for simultaneously detecting multiple stimulants in animal food 石家庄海关技术中心 2021-12-21 — — CN claimed
CN-117858663-A Films with biodegradable polymers 豪夫迈·罗氏有限公司 2024-04-09 — — CN disclosed
CN-117849228-A Biomarker for screening early sexual precocity and application thereof 裕菁科技(上海)有限公司 2024-04-09 — — CN disclosed
US-20230330084-A1 HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS CORCEPT THERAPEUTICS, INC. (US) 2023-10-19 — — US disclosed
CN-111527407-B Method for detecting immune related disease index 株式会社漫丹 2023-09-15 — — CN disclosed
CN-116602911-A Hollow rectal suppository containing medicine 中国人民解放军军事科学院军事医学研究院 2023-08-18 — — CN disclosed
CN-116437928-A Pharmaceutical composition for preventing, inhibiting or treating symptoms associated with allergic reactions 日本化学药品株式会社 2023-07-14 — — CN disclosed
CN-110339346-B External skin preparation composition IGISU株式会社 2023-06-27 — — CN disclosed
US-11648245-B2 Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators CORCEPT THERAPEUTICS, INC. (US) 2023-05-16 — — US disclosed
CN-116018131-A Fast orodispersible tablet with inner cavity 阿普雷奇亚制药有限责任公司 2023-04-25 — — CN disclosed
EP-2489339-A1 METHOD AND DEVICE FOR PRODUCING ADHESIVE PATCH Hisamitsu Pharmaceutical Co., Inc. (JP) 2012-08-22 — — EP disclosed
EP-2489340-A1 ADHESIVE PATCH Hisamitsu Pharmaceutical Co., Inc. (JP) 2012-08-22 — — EP disclosed
WO-2012094618-A1 COMBINATION STEROID AND GLUCOCORTICOID RECEPTOR ANTAGONIST THERAPY CORCEPT THERAPEUTICS, INC. (US) 2012-07-12 — — WO disclosed
CN-102573722-A A preparation method of adhesive patch and a device thereof HISAMITSU PHARMACEUTICAL CO 2012-07-11 — — CN disclosed
CN-102573723-A Adhesive patch HISAMITSU PHARMACEUTICAL INC 2012-07-11 — — CN disclosed
US-20110130704-A1 COMBINATION OF A LIGHT RAY AND A LIPASE-BIOCONVERTIBLE COMPOUND FOR IMPROVING SKIN AND/OR HAIR APPEARANCE L'OREAL (FR) 2011-06-02 — — US disclosed
EP-2177513-A1 PHENYLACETIC ACID COMPOUND ONO Pharmaceutical Co., Ltd. (JP) 2010-04-21 — — EP disclosed
US-20090275668-A1 Sprayable Gel-Type Skin/Mucosa-Adhesive Preparation and Administration System Using the Preparation TOKO YAKUHIN KOGYO DABUSHIKI KAISHA (JP) 2009-11-05 — — US disclosed
US-20030138479-A1 Plaster HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2003-07-24 — — US disclosed
EP-1293199-A1 PLASTER HISAMITSU PHARMACEUTICAL CO. INC. (JP) 2003-03-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11648245-B2 Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators NR3C1, GRIN3A, NR3C2 NR3C1 1/4885PGR 186/4885CYP3A4 1984/4885
US-20230330084-A1 HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS NR3C1, GRIN3A, NR3C2 NR3C1 1/4885PGR 186/4885CYP3A4 1984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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