Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.65 |
| ▸ | FBP1 | P09467 | 3/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19436972 | 1.00 | AKR1C3 (0.65) | AKR1C3FBP1AKR1C1AKR1C2CYP1B1 | |
| SCHEMBL7813612 | 0.84 | AKR1C1 (0.66) | AKR1C3AKR1C1AKR1C2CYP1B1ALDH1A1 | |
| SCHEMBL7813609 | 0.84 | AKR1C1 (0.66) | AKR1C3AKR1C1AKR1C2CYP1B1ALDH1A1 | |
| SCHEMBL15777306 | 0.84 | AKR1C1 (0.66) | AKR1C3AKR1C1AKR1C2CYP1B1ALDH1A1 | |
| SCHEMBL11216772 | 0.81 | MAPT (0.62) | FBP1AKR1C1ALDH1A1MAOBMEN1 | |
| SCHEMBL7828363 | 0.81 | MAPT (0.62) | FBP1AKR1C1ALDH1A1MAOBMEN1 | |
| SCHEMBL7828360 | 0.81 | MAPT (0.62) | FBP1AKR1C1ALDH1A1MAOBMEN1 | |
| SCHEMBL11218795 | 0.79 | AKR1C1 (0.66) | AKR1C3FBP1AKR1C1AKR1C2CYP1B1 | |
| SCHEMBL11220467 | 0.79 | AKR1C1 (0.66) | AKR1C3FBP1AKR1C1AKR1C2CYP1B1 | |
| SCHEMBL11220464 | 0.79 | AKR1C1 (0.66) | AKR1C3FBP1AKR1C1AKR1C2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017176930-A1 | DIPHENYLACRYLIC ACID DERIVATIVES THAT PROMOTE BONE AND CARTILAGE GROWTH | EMORY UNIVERSITY (US) | 2017-10-12 | — | — | WO | claimed |