Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.60 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828363 | 1.00 | MAPT (0.62) | MAPTMAOBLMNAAKR1C1GLO1 | |
| SCHEMBL7828360 | 1.00 | MAPT (0.62) | MAPTMAOBLMNAAKR1C1GLO1 | |
| SCHEMBL11222306 | 0.90 | FBP1 (0.62) | MAPTMAOBLMNAGLO1NFE2L2 | |
| SCHEMBL11222310 | 0.90 | FBP1 (0.62) | MAPTMAOBLMNAGLO1NFE2L2 | |
| SCHEMBL7813609 | 0.83 | AKR1C1 (0.66) | MAPTMAOBAKR1C1ALDH1A1MEN1 | |
| SCHEMBL11218795 | 0.83 | AKR1C1 (0.66) | MAPTMAOBAKR1C1FBP1ALDH1A1 | |
| SCHEMBL11220467 | 0.83 | AKR1C1 (0.66) | MAPTMAOBAKR1C1FBP1ALDH1A1 | |
| SCHEMBL15777306 | 0.83 | AKR1C1 (0.66) | MAPTMAOBAKR1C1ALDH1A1MEN1 | |
| SCHEMBL11220464 | 0.83 | AKR1C1 (0.66) | MAPTMAOBAKR1C1FBP1ALDH1A1 | |
| SCHEMBL28236366 | 0.83 | NFE2L2 (0.63) | MAPTMAOBLMNAGLO1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342781-A | PREVENTING AND TREATING ALLERGIC BRONCHIAL ASTHMA, RHINITIS AND SKIN DISORDERS | PFIZER INC. (US) | 1982-08-03 | — | — | US | disclosed |