Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.50 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.50 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.50 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12934598 | 0.92 | HPGD (0.53) | HPGDCES2CES1MAPTRAB9A | |
| SCHEMBL13531604 | 0.92 | CES2 (0.56) | HPGDCES2CES1MAPTRAB9A | |
| SCHEMBL16595406 | 0.91 | CES2 (0.52) | HPGDCES2CES1MAPTRAB9A | |
| SCHEMBL22407070 | 0.91 | HPGD (0.53) | HPGDCES2CES1MAPTRAB9A | |
| SCHEMBL2122107 | 0.87 | CES2 (0.75) | CES2CES1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9041291 | 0.83 | MAPT (0.65) | MAPTRAB9ASMN1; SMN2PARP10KMT2A | |
| SCHEMBL31135476 | 0.82 | ELANE (0.56) | CES2CES1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9041763 | 0.82 | MAPT (0.67) | CES2CES1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20252722 | 0.81 | CA1 (0.67) | HPGDCES2CES1MAPTRAB9A | |
| SCHEMBL29245017 | 0.80 | CES2 (0.48) | CES2CES1MAPTALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879925-B1 | PHENYLGLYOXALIC ESTERS GENERATING BY PHOTOLYSIS LOW MIGRATABLE FRAGMENTS | LAMBERTI SPA (IT) | 2011-06-15 | — | — | EP | disclosed |
| EP-1879925-B1 | PHENYLGLYOXALIC ESTERS GENERATING BY PHOTOLYSIS LOW MIGRATABLE FRAGMENTS | LAMBERTI SPA (IT) | 2011-06-15 | — | — | EP | disclosed |
| US-7868054-B2 | Phenylglyoxalic esters generated by photolysis of low migratable fragments | LAMBERTI SPA (IT) | 2011-01-11 | — | — | US | disclosed |
| US-7868054-B2 | Phenylglyoxalic esters generated by photolysis of low migratable fragments | LAMBERTI SPA (IT) | 2011-01-11 | — | — | US | disclosed |
| US-20080193677-A1 | Phenylglyoxalic Esters Generating by Photolysis Low Migratable Fragments | IGM RESINS ITALIA S.R.L. (IT) | 2008-08-14 | — | — | US | disclosed |
| US-20080193677-A1 | Phenylglyoxalic Esters Generating by Photolysis Low Migratable Fragments | IGM RESINS ITALIA S.R.L. (IT) | 2008-08-14 | — | — | US | disclosed |