SCHEMBL19437438

SCHEMBL19437438

[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCC(=O)NCCOCCOCCOCCOCCOCCN

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.37
CA2 P00918 6/20 0.36
CA9 Q16790 5/20 0.36
CA12 O43570 4/20 0.36
CA1 P00915 4/20 0.36
CA4 P22748 4/20 0.36
CA14 Q9ULX7 4/20 0.36
HDAC3 O15379 1/20 0.34
HDAC1 Q13547 1/20 0.34
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MGMT P16455 1/20 0.31
PLK1 P53350 2/20 0.31
TTR P02766 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25356799 0.91 CRBN (0.34) CRBNCA2CA9CA12CA1
SCHEMBL16329564 0.90 CRBN (0.33) CRBNCA2CA9CA12CA1
SCHEMBL24297232 0.90 CRBN (0.33) CRBNCA2CA9CA12CA1
SCHEMBL24296991 0.89 CRBN (0.33) CRBNCA2CA9CA12CA1
SCHEMBL24297328 0.89 CRBN (0.33) CRBNCA2CA9CA12CA1
SCHEMBL24296994 0.89 CRBN (0.33) CRBNCA2CA9CA12CA1
SCHEMBL24920307 0.89 TSHR (0.35) CRBNCA2CA9CA12CA1
SCHEMBL18886281 0.88 CRBN (0.41) CRBNCA2CA9CA12CA1
SCHEMBL17282361 0.88 CRBN (0.41) CRBNCA2CA9CA12CA1
SCHEMBL19818387 0.87 HPSE (0.36) CRBNCA2CA9CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3736572-B1 INTRA-DROPLET SURFACE ENGINEERING TO CAPTURE A MOLECULAR TARGET UNIV STRASBOURG (FR) 2024-07-24 EP disclosed
CN-115368916-A Droplet interior surface engineering for capture of molecular targets 斯特拉斯堡大学 2022-11-22 CN disclosed
CN-109073647-B Droplet interior surface engineering for capture of molecular targets 斯特拉斯堡大学 2022-07-12 CN disclosed
US-20220074930-A1 INTRA-DROPLET SURFACE ENGINEERING TO CAPTURE A MOLECULAR TARGET UNIVERSITE DE STRASBOURG (FR) 2022-03-10 US disclosed
US-11181521-B2 Intra-droplet surface engineering to capture a molecular target UNIVERSITE DE STRASBOURG (FR) 2021-11-23 US disclosed
EP-3736572-A1 INTRA-DROPLET SURFACE ENGINEERING TO CAPTURE A MOLECULAR TARGET Université de Strasbourg (FR) 2020-11-11 EP disclosed
EP-3440463-B1 INTRA-DROPLET SURFACE ENGINEERING TO CAPTURE A MOLECULAR TARGET UNIV STRASBOURG (FR) 2020-07-08 EP disclosed
US-20190113509-A1 INTRA-DROPLET SURFACE ENGINEERING TO CAPTURE A MOLECULAR TARGET CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2019-04-18 US disclosed
EP-3440463-A1 INTRA-DROPLET SURFACE ENGINEERING TO CAPTURE A MOLECULAR TARGET Université de Strasbourg (FR) 2019-02-13 EP disclosed
WO-2017174610-A1 INTRA-DROPLET SURFACE ENGINEERING TO CAPTURE A MOLECULAR TARGET UNIVERSITE DE STRASBOURG (FR) 2017-10-12 WO disclosed
WO-2017174610-A1 INTRA-DROPLET SURFACE ENGINEERING TO CAPTURE A MOLECULAR TARGET UNIVERSITE DE STRASBOURG (FR) 2017-10-12 WO disclosed