Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | MGMT | P16455 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076070 | 0.94 | SLC6A5 (0.40) | TSHRSLC6A5CRBNKDM4AHIF1A | |
| SCHEMBL17316218 | 0.94 | HDAC6 (0.37) | SLC6A5HPSECA12CA1CA2 | |
| SCHEMBL25356799 | 0.91 | CRBN (0.34) | TSHRCRBNCA12CA1CA2 | |
| SCHEMBL20375128 | 0.89 | SLC6A5 (0.36) | TSHRSLC6A5KDM4AHIF1ATET2 | |
| SCHEMBL29328700 | 0.89 | TSHR (0.35) | TSHRCRBNHPSECA12CA1 | |
| SCHEMBL19437438 | 0.89 | CRBN (0.37) | CRBNPLK1CA12CA1CA2 | |
| SCHEMBL13497895 | 0.87 | SLC6A5 (0.44) | SLC6A5CRBNKDM4AHIF1ATET2 | |
| SCHEMBL25841787 | 0.86 | SLC6A5 (0.40) | TSHRSLC6A5CRBNHPSECA12 | |
| SCHEMBL24920285 | 0.85 | CA1 (0.31) | CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL29406774 | 0.84 | CD40 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006782-A1 | CONJUGATING REAGENTS AND CONJUGATES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2023-02-02 | — | — | WO | disclosed |