SCHEMBL1944113

SCHEMBL1944113

O=C(Oc1ccc(OC(=O)C(O)(c2ccccc2)c2ccccc2)c2ccccc12)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 6/20 0.43
CHRM2 P08172 5/20 0.43
CHRM1 P11229 4/20 0.43
CHRM4 P08173 2/20 0.43
CHRM5 P08912 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 2/20 0.40
KCNN4 O15554 1/20 0.40
ALDH1A1 P00352 1/20 0.40
JAK2 O60674 1/20 0.40
USP2 O75604 1/20 0.40
ESR1 P03372 1/20 0.40
GAA P10253 1/20 0.40
ALOX15 P16050 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ESR2 Q92731 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23856076 0.81 PTGDR2 (0.50) CHRM3CHRM2CHRM1MEN1KMT2A
SCHEMBL4579643 0.79 KDM4E (0.57) CHRM3MEN1KMT2AMAPTALDH1A1
SCHEMBL6599026 0.79 CHRM3 (0.45) CHRM3CHRM2CHRM1CHRM4CHRM5
SCHEMBL9250738 0.79 ELANE (0.49) CHRM3CHRM2CHRM1CHRM4CHRM5
SCHEMBL23440876 0.77 PTGDR2 (0.40) CHRM3KMT2AMAPTKCNN4ALDH1A1
SCHEMBL1870824 0.76 KCNN4 (0.67) CHRM3CHRM2CHRM1CHRM4MEN1
SCHEMBL1986527 0.76 CHRM3 (0.46) CHRM3CHRM2CHRM1CHRM4CHRM5
SCHEMBL11878020 0.76 CHRM3 (0.49) CHRM3CHRM2CHRM1CHRM4CHRM5
SCHEMBL6130411 0.74 KMT2A (0.56) MEN1KMT2AMAPTALDH1A1ESR1
SCHEMBL2638148 0.73 ESR1 (0.48) MEN1KMT2AMAPTALDH1A1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1900541-B1 Heat-sensitive recording material and production method thereof RICOH CO LTD (JP) 2014-08-13 EP disclosed
US-8168565-B2 Thermal recording adhesive label RICOH COMPANY, LTD. (JP) 2012-05-01 US disclosed
US-8147905-B2 Heat-sensitive recording material and production method thereof RICOH COMPANY, LTD. (JP) 2012-04-03 US disclosed
US-20110135830-A1 HEAT-SENSITIVE RECORDING MATERIAL AND PRODUCTION METHOD THEREOF RICOH COMPANY, LTD. (JP) 2011-06-09 US disclosed
US-7906458-B2 Color developing layer on a substrate, containing a leuco dye and a developer; protective layer of a binder resin, of diacetone-modified polyvinyl alcohol resin RICOH COMPANY, LTD. (JP) 2011-03-15 US disclosed
US-20090209419-A1 THERMAL RECORDING ADHESIVE LABEL RICOH COMPANY, LTD. (JP) 2009-08-20 US disclosed
US-20080146443-A1 Heat-sensitive recording material and production method thereof RICOH COMPANY, LTD. (JP) 2008-06-19 US disclosed
EP-1900541-A1 Heat-sensitive recording material and production method thereof RICOH Co., Ltd. (JP) 2008-03-19 EP disclosed
EP-1243437-B1 Leuco dye dispersion liquid and thermosensitive recording material using the same RICOH KK (JP) 2004-11-17 EP disclosed