SCHEMBL19441727

CC(=O)NCC(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](C)C(=O)N[C@H](CCCCNC(=N)N)C(=O)N[C@H](C)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](C)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](C)C(=O)N[C@H](CCCCNC(=N)N)C(=O)N[C@H](CS)C(N)=O

nearest known ligand 0.49

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	15/20	0.49

▸	NPY5R	Q15761	9/20	0.49

▸	NPY1R	P25929	9/20	0.49

▸	NPY2R	P49146	6/20	0.43

▸	SIRT5	Q9NXA8	2/20	0.43

▸	NPBWR1	P48145	1/20	0.39

▸	IL23R	Q5VWK5	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20799359	0.90	SIRT5 (0.45)	NPY4RNPY5RNPY1RNPY2RSIRT5
SCHEMBL20724927	0.90	NPY4R (0.46)	NPY4RNPY5RNPY1RNPY2RSIRT5
SCHEMBL17349855	0.89	NPY4R (0.46)	NPY4RNPY5RNPY1RNPY2RSIRT5
SCHEMBL17349979	0.89	NPY4R (0.46)	NPY4RNPY5RNPY1RNPY2RSIRT5
SCHEMBL20799368	0.88	NPY4R (0.46)	NPY4RNPY5RNPY1RNPY2RSIRT5
SCHEMBL12035314	0.87	NPY4R (0.48)	NPY4RNPY5RNPY1RNPY2RSIRT5
SCHEMBL20799372	0.87	NPY4R (0.46)	NPY4RNPY5RNPY1RNPY2RSIRT5
SCHEMBL12035268	0.86	NPY4R (0.46)	NPY4RNPY5RNPY1RNPY2RSIRT5
SCHEMBL17849801	0.86	NPY4R (0.44)	NPY4RNPY5RNPY1RNPY2RSIRT5
SCHEMBL17849817	0.85	NPY4R (0.47)	NPY4RNPY5RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9782498-B2	Selective delivery molecules and methods of use	AVELAS BIOSCIENCES, INC. (US)	2017-10-10	—	—	US	disclosed