Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19443187 | 0.92 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL19443205 | 0.83 | DGAT1 (0.52) | DGAT1 | |
| SCHEMBL14137123 | 0.80 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL17200594 | 0.80 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL14137119 | 0.80 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL14137323 | 0.79 | DGAT1 (0.74) | DGAT1 | |
| SCHEMBL17200587 | 0.79 | DGAT1 (0.74) | DGAT1 | |
| SCHEMBL14137214 | 0.75 | DGAT1 (0.84) | DGAT1 | |
| SCHEMBL14061873 | 0.75 | DGAT1 (0.84) | DGAT1 | |
| SCHEMBL15711534 | 0.75 | DGAT1 (0.58) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2916839-B1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2017-10-11 | — | — | EP | disclosed |