Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 4/20 | 0.92 |
| ▸ | ALB | P02768 | 2/20 | 0.92 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.92 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.92 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.92 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.92 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.92 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.92 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.92 |
| ▸ | DRD3 | P35462 | 1/20 | 0.92 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.92 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.84 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpidem SCHEMBL122619 | 0.96 | TSPO (1.00) | TSPOALBOPRK1KCNH2NR1I2 | |
| Alpidem SCHEMBL4014704 | 0.93 | TSPO (0.83) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL6642731 | 0.92 | TSPO (0.88) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL13217826 | 0.91 | TSPO (0.76) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL23624269 | 0.90 | TSPO (0.88) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL23624249 | 0.89 | TSPO (0.86) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL23624329 | 0.87 | TSPO (0.83) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL23624214 | 0.86 | TSPO (0.81) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL6643201 | 0.85 | TSPO (0.77) | TSPOALBOPRK1KCNH2NR1I2 | |
| SCHEMBL3035751 | 0.85 | TSPO (0.78) | TSPOALBOPRK1KCNH2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2752415-B1 | Fluorinated ligands for targeting peripheral benzodiazepine receptors | AUSTRALIAN NUCLEAR SCIENCE & TECH ORGANISATION (AU) | 2017-10-11 | — | — | EP | disclosed |