Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 4/20 | 0.69 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | ALB | P02768 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.67 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.62 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034122 | 0.98 | TSPO (0.71) | TSPONR1I2ABCB11ALBADORA3 | |
| SCHEMBL13238060 | 0.94 | TSPO (0.71) | TSPONR1I2ABCB11ALBADORA3 | |
| SCHEMBL3033510 | 0.94 | TSPO (0.65) | TSPONR1I2ABCB11ALBADORA3 | |
| SCHEMBL3030876 | 0.93 | TSPO (0.64) | TSPONR1I2ABCB11ALBADORA3 | |
| SCHEMBL13217938 | 0.93 | TSPO (0.64) | TSPONR1I2ABCB11ALBADORA3 | |
| SCHEMBL3024469 | 0.93 | TSPO (0.66) | TSPONR1I2ABCB11ALBADORA3 | |
| SCHEMBL3030326 | 0.92 | TSPO (0.68) | TSPONR1I2ABCB11ALBADORA3 | |
| SCHEMBL3026471 | 0.92 | TSPO (0.63) | TSPONR1I2ABCB11ALBADORA3 | |
| SCHEMBL13217935 | 0.92 | TSPO (0.65) | TSPONR1I2ABCB11ALBADORA3 | |
| SCHEMBL3022530 | 0.92 | TSPO (0.65) | TSPONR1I2ABCB11ALBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2752415-B1 | Fluorinated ligands for targeting peripheral benzodiazepine receptors | AUSTRALIAN NUCLEAR SCIENCE & TECH ORGANISATION (AU) | 2017-10-11 | — | — | EP | disclosed |