Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19433129 | 1.00 | BLM (0.36) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL19433131 | 0.91 | LMNA (0.41) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL19433125 | 0.88 | TYR (0.39) | BLMNPSR1TSHRKMT2ACYP3A4 | |
| SCHEMBL19433106 | 0.88 | TYR (0.39) | BLMNPSR1TSHRKMT2ACYP3A4 | |
| SCHEMBL19444468 | 0.82 | BLM (0.35) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL19444291 | 0.76 | TYR (0.44) | TSHRUSP2KMT2ACYP3A4MEN1 | |
| SCHEMBL12669642 | 0.75 | BLM (0.47) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL28166976 | 0.73 | AKR1B1 (0.41) | BLMNPSR1TSHRLMNAUSP2 | |
| SCHEMBL9988674 | 0.71 | TYR (0.47) | BLMNPSR1TSHRLMNAMAPK1 | |
| SCHEMBL7458752 | 0.71 | TYR (0.47) | BLMNPSR1TSHRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3228301-A1 | HAIR SHAPING AGENT | Kao Corporation (JP) | 2017-10-11 | — | — | EP | disclosed |