Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNB1 | Q14721 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | CLPP | Q16740 | 1/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445719 | 0.93 | KLKB1 (0.41) | MMP2TSHRKCNB1KMT2AMEN1 | |
| SCHEMBL10262149 | 0.89 | ERAP2 (0.43) | MMP2TSHRKLKB1 | |
| SCHEMBL13978369 | 0.87 | ALDH1A1 (0.44) | MMP2TSHRKCNB1KMT2AMEN1 | |
| SCHEMBL10199166 | 0.86 | FFAR1 (0.41) | MMP2TSHRKCNB1KCNA5KCNK2 | |
| SCHEMBL10261894 | 0.86 | ERAP2 (0.43) | MMP2TSHRKCNB1KMT2AMEN1 | |
| SCHEMBL10262460 | 0.86 | ERAP2 (0.43) | MMP2TSHRKCNB1KMT2AMEN1 | |
| SCHEMBL10260677 | 0.85 | KLKB1 (0.41) | MMP2TSHRKCNB1KMT2AMEN1 | |
| SCHEMBL19445517 | 0.84 | NPY4R (0.40) | MMP2TSHRF2 | |
| SCHEMBL21371608 | 0.84 | ERAP2 (0.46) | MMP2TSHRKLKB1 | |
| SCHEMBL21371927 | 0.84 | KLKB1 (0.41) | MMP2TSHRKCNB1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |