Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 10/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.49 |
| ▸ | EGFR | P00533 | 9/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335840 | 0.84 | HDAC3 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8445092 | 0.80 | ALDH1A1 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6579751 | 0.80 | ALDH1A1 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6581661 | 0.80 | ALDH1A1 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8844788 | 0.80 | ALDH1A1 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL17614784 | 0.80 | ALDH1A1 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13536389 | 0.77 | HDAC3 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7569662 | 0.76 | ALDH1A1 (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29401086 | 0.76 | ALDH1A1 (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6579889 | 0.75 | HDAC1 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |