Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445568 | 1.00 | MAPK14 (0.38) | MAPK14SMYD3ALDH1A1KMT2AGPR55 | |
| SCHEMBL19445570 | 1.00 | MAPK14 (0.38) | MAPK14SMYD3ALDH1A1KMT2AGPR55 | |
| SCHEMBL10268065 | 0.95 | MAPK14 (0.41) | MAPK14ALDH1A1KMT2AGPR55KDM4E | |
| SCHEMBL12515350 | 0.95 | MAPK14 (0.41) | MAPK14ALDH1A1KMT2AGPR55KDM4E | |
| SCHEMBL19445653 | 0.93 | MAPK14 (0.34) | MAPK14SMYD3ALDH1A1KMT2AGPR55 | |
| SCHEMBL13973796 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KMT2AGPR55KDM4ERAB9A | |
| SCHEMBL19445884 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KMT2AGPR55KDM4ERAB9A | |
| SCHEMBL10268073 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KMT2AGPR55KDM4ERAB9A | |
| SCHEMBL21864859 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KMT2AGPR55KDM4ERAB9A | |
| SCHEMBL12515252 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KMT2AGPR55KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |