Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19446260 | 0.78 | GAA (0.42) | KMT2AMEN1TSHRSIGMAR1LMNA | |
| SCHEMBL17285638 | 0.77 | KMT2A (0.56) | KMT2AMEN1TSHRNPSR1SIGMAR1 | |
| SCHEMBL24319647 | 0.77 | KMT2A (0.56) | KMT2AMEN1TSHRNPSR1SIGMAR1 | |
| SCHEMBL24319645 | 0.77 | KMT2A (0.56) | KMT2AMEN1TSHRNPSR1SIGMAR1 | |
| SCHEMBL19446304 | 0.76 | USP2 (0.53) | KMT2AMEN1TSHRLMNAUSP2 | |
| SCHEMBL7278149 | 0.76 | KMT2A (0.46) | KMT2AMEN1TSHRNPSR1SIGMAR1 | |
| SCHEMBL19446303 | 0.73 | MEN1 (0.44) | KMT2AMEN1TSHRNPSR1SIGMAR1 | |
| SCHEMBL10130274 | 0.72 | MEN1 (0.42) | KMT2AMEN1TSHRNPSR1SIGMAR1 | |
| SCHEMBL22544217 | 0.72 | MEN1 (0.50) | KMT2AMEN1TSHRNPSR1SIGMAR1 | |
| SCHEMBL12424417 | 0.72 | MEN1 (0.50) | KMT2AMEN1TSHRNPSR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3039010-B1 | ARYL NAPHTHYL METHANONE OXIME(S) AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2017-10-11 | — | — | EP | disclosed |