Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21675573 | 1.00 | POLB (0.51) | POLBCA1CA2CA4CA9 | |
| SCHEMBL14986325 | 0.80 | POLB (0.51) | POLBCA1CA2CA4CA9 | |
| SCHEMBL11386097 | 0.80 | POLB (0.51) | POLBCA1CA2CA4CA9 | |
| SCHEMBL1368801 | 0.80 | POLB (0.51) | POLBCA1CA2CA4CA9 | |
| SCHEMBL17170027 | 0.80 | POLB (0.47) | POLBCA1CA2CA4CA9 | |
| SCHEMBL4658509 | 0.80 | POLB (0.47) | POLBCA1CA2CA4CA9 | |
| SCHEMBL13888957 | 0.80 | POLB (0.47) | POLBCA1CA2CA4CA9 | |
| SCHEMBL18325 | 0.79 | LTA4H (0.61) | POLBCA1CA2CA4CA9 | |
| SCHEMBL3491795 | 0.79 | LTA4H (0.61) | POLBCA1CA2CA4CA9 | |
| SCHEMBL24350 | 0.79 | LTA4H (0.61) | POLBCA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794611-B1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2017-10-11 | — | — | EP | disclosed |