Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15073052 | 0.91 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL19447482 | 0.86 | KMT2A (0.36) | KMT2A | |
| SCHEMBL2737741 | 0.85 | HCRTR1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL15073045 | 0.85 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL19447307 | 0.85 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL2738210 | 0.85 | GRM5 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL2737735 | 0.84 | HCRTR1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL15072884 | 0.84 | GRM5 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL19447601 | 0.84 | GRM5 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL19447310 | 0.84 | GPBAR1 (0.37) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794611-B1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2017-10-11 | — | — | EP | disclosed |