Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15072877 | 0.80 | CCR2 (0.40) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL2920433 | 0.80 | CCR2 (0.40) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL23459089 | 0.79 | GLI1 (0.36) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL19447676 | 0.79 | GRIN2D (0.32) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL13732366 | 0.77 | SCN9A (0.37) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL15432264 | 0.77 | SCN9A (0.37) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL12312784 | 0.76 | CCR2 (0.43) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL12337422 | 0.76 | CCR2 (0.44) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL15077300 | 0.76 | CCR2 (0.44) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL2912163 | 0.74 | DPP7 (0.35) | GRIN2DGRIN3BTHRBGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794611-B1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2017-10-11 | — | — | EP | disclosed |