SCHEMBL19448995

SCHEMBL19448995

c1ccc(-c2ccc(N(c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-4)c3ccc4c(c3)oc3cc(-c5ccccc5)ccc34)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
OPRK1 P41145 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MMP12 P39900 1/20 0.30
MMP13 P45452 1/20 0.30
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24255914 0.96 MMP12 (0.35) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL24923304 0.96 MMP12 (0.35) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL23628265 0.95 PDK2 (0.32) PDK2MEN1KMT2ATHRBRECQL
SCHEMBL24255765 0.94 AHR (0.33) PDK2MEN1KMT2ATHRBRECQL
SCHEMBL21039286 0.94 MEN1 (0.35) PDK2MEN1KMT2ATHRBRECQL
SCHEMBL21039284 0.94 MEN1 (0.35) PDK2MEN1KMT2ATHRBRECQL
SCHEMBL22155858 0.94 PDK2 (0.38) PDK2MEN1KMT2ATHRBRECQL
SCHEMBL21558973 0.94 MMP12 (0.34) PDK2MEN1KMT2AKDM4EMAPT
SCHEMBL17735311 0.94 MMP12 (0.34) PDK2MEN1KMT2AKDM4EMAPT
SCHEMBL22150231 0.93 MEN1 (0.33) PDK2MEN1KMT2ATHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170294587-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 US disclosed
US-20170294587-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 US disclosed