SCHEMBL19449085

SCHEMBL19449085

CC(C)(C)C(=O)Oc1ccc2c(c1)Oc1cc(OC(=O)C(C)(C)C)ccc1C21OC(=O)c2cc(C(=O)NCCCOCC(O)CO)ccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GSTP1 P09211 1/20 0.46
▸ MAPT P10636 3/20 0.43
▸ HTT P42858 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ USP2 O75604 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ LMNA P02545 1/20 0.43
▸ ITPR3 Q14573 1/20 0.42
▸ MMP14 P50281 1/20 0.40
▸ KCNH2 Q12809 3/20 0.40
▸ ALB P02768 1/20 0.40
▸ CYP3A4 P08684 1/20 0.38
▸ FTO Q9C0B1 6/20 0.37
▸ HPGD P15428 3/20 0.35
▸ GAA P10253 1/20 0.35
▸ JAK2 O60674 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19449086 0.87 GSTP1 (0.39) GSTP1MAPTHTTKMT2AMEN1
SCHEMBL19749369 0.87 GSTP1 (0.43) GSTP1MAPTHTTKMT2AMEN1
SCHEMBL6879196 0.86 GSTP1 (0.50) GSTP1MAPTHTTKMT2AMEN1
SCHEMBL19431854 0.86 GSTP1 (0.47) GSTP1MAPTHTTKMT2AMEN1
SCHEMBL22403837 0.85 HPGD (0.37) GSTP1MAPTHTTKMT2ALMNA
SCHEMBL13237871 0.83 GSTP1 (0.49) GSTP1MAPTHTTKMT2AMEN1
SCHEMBL13881238 0.83 GSTP1 (0.46) GSTP1MAPTHTTKMT2AMEN1
SCHEMBL12964684 0.81 ALB (0.44) GSTP1MAPTHTTKMT2AMEN1
SCHEMBL4403236 0.80 GSTP1 (0.45) GSTP1MAPTHTTKMT2AMEN1
SCHEMBL19431893 0.78 GSTP1 (0.41) GSTP1MAPTHTTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3455299-B1 COMPOSITIONS COMPRISING A POLYMERIC DYE AND A CYCLODEXTRIN AND USES THEREOF SONY GROUP CORP (JP) 2024-01-17 — — EP disclosed
US-11874280-B2 Use of divalent metals for enhancement of fluorescent signals Sony Group Corporation (JP) 2024-01-16 — — US disclosed
WO-2023242661-A2 POLYMERIC TANDEM DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-12-21 — — WO disclosed
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-04-27 — — US disclosed
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-04-27 — — US disclosed
EP-4137818-A1 USE OF DIVALENT METALS FOR ENHANCEMENT OF FLUORESCENT SIGNALS Sony Group Corporation (JP) 2023-02-22 — — EP disclosed
US-20210096135-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2021-04-01 — — US disclosed
US-10866244-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups SONY CORPORATION OF AMERICA (US) 2020-12-15 — — US disclosed
WO-2019182765-A1 USE OF DIVALENT METALS FOR ENHANCEMENT OF FLUORESCENT SIGNALS SONY CORPORATION (JP) 2019-09-26 — — WO disclosed
US-20190136065-A1 COMPOSITIONS COMPRISING A POLYMERIC DYE AND A CYCLODEXTRIN AND USES THEREOF Sony Group Corporation (JP) 2019-05-09 — — US disclosed
US-20180164322-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2018-06-14 — — US disclosed
US-20180164322-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2018-06-14 — — US disclosed
US-9851359-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups SONY CORPORATION OF AMERICA (US) 2017-12-26 — — US disclosed
US-9851359-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups SONY CORPORATION OF AMERICA (US) 2017-12-26 — — US disclosed
US-20170292957-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2017-10-12 — — US disclosed
US-20170292957-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2017-10-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10866244-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups IK, MTCL3, RRM1 GSTP1 3586/4885MAPT 6/4885HTT 368/4885
US-20180164322-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 GSTP1 3586/4885MAPT 6/4885HTT 368/4885
US-20210096135-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 GSTP1 3586/4885MAPT 6/4885HTT 368/4885
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 GSTP1 3586/4885MAPT 6/4885HTT 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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