Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO1 | P00395 | 2/20 | 0.84 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.84 |
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19449242 | 0.91 | MT-CO1 (1.00) | MT-CO1MT-CO2EDNRAOPRM1HTR2B | |
| SCHEMBL19449212 | 0.87 | MT-CO1 (0.64) | MT-CO1MT-CO2EDNRAOPRM1HTR2B | |
| SCHEMBL21844902 | 0.82 | MT-CO1 (0.79) | MT-CO1MT-CO2EDNRAOPRM1HTR2B | |
| SCHEMBL19449277 | 0.82 | MT-CO1 (0.75) | MT-CO1MT-CO2EDNRAOPRM1HTR2B | |
| SCHEMBL19449213 | 0.81 | MT-CO1 (0.59) | MT-CO1MT-CO2EDNRAOPRM1HTR2B | |
| SCHEMBL19449224 | 0.81 | MT-CO1 (0.69) | MT-CO1MT-CO2EDNRAOPRM1HTR2B | |
| SCHEMBL19449235 | 0.80 | MT-CO1 (0.85) | MT-CO1MT-CO2EDNRAOPRM1HTR2B | |
| SCHEMBL19449244 | 0.78 | MT-CO1 (0.76) | MT-CO1MT-CO2EDNRAOPRM1HTR2B | |
| SCHEMBL19449221 | 0.78 | MT-CO1 (0.67) | MT-CO1MT-CO2HSP90AA1PAX8RAB9A | |
| SCHEMBL19449245 | 0.72 | MT-CO1 (0.69) | MT-CO1MT-CO2EDNRAOPRM1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170290830-A1 | SMALL MOLECULE REGULATORS OF STEROID RECEPTOR COACTIVATORS AND METHODS OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290830-A1 | SMALL MOLECULE REGULATORS OF STEROID RECEPTOR COACTIVATORS AND METHODS OF USE THEREOF | NCOA2, NCOA3, NCOA1 | MT-CO1 2559/4885MT-CO2 3459/4885EDNRA 2703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.