Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19437798 | 0.87 | THRB (0.44) | CNR2CYP3A4 | |
| SCHEMBL19437960 | 0.87 | THRB (0.44) | CNR2CYP3A4 | |
| SCHEMBL19437797 | 0.87 | THRB (0.44) | CNR2CYP3A4 | |
| SCHEMBL19437971 | 0.85 | MAPT (0.41) | — | |
| SCHEMBL19437768 | 0.85 | CNR2 (0.41) | CNR2CNR1GRM5 | |
| SCHEMBL19449582 | 0.84 | CNR2 (0.43) | CNR2CNR1GRM5 | |
| SCHEMBL19438022 | 0.84 | IDH1 (0.42) | CNR2CNR1TACR3 | |
| SCHEMBL19438021 | 0.84 | IDH1 (0.42) | CNR2CNR1TACR3 | |
| SCHEMBL19438260 | 0.83 | ADORA2A (0.39) | GSK3BDYRK1A | |
| SCHEMBL19438275 | 0.82 | GSK3B (0.38) | GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017176961-A1 | IMIDAZO [1,5-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | LYSOSOMAL THERAPEUTICS INC. (US) | 2017-10-12 | — | — | WO | disclosed |