SCHEMBL1945085

SCHEMBL1945085

COc1c(-c2ccccc2)c2cc3nc(cc4ccc(cc5nc(cc1[nH]2)C=C5)[nH]4)C=C3

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.49
▸ STAT1 P42224 1/20 0.49
▸ TP53 P04637 3/20 0.38
▸ KDM4E B2RXH2 3/20 0.38
▸ TSHR P16473 2/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ NPC1 O15118 2/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ NFKB2 Q00653 1/20 0.38
▸ RELA Q04206 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ MAPT P10636 5/20 0.36
▸ PDE4B Q07343 4/20 0.36
▸ PDE4A P27815 3/20 0.36
▸ PDE4C Q08493 3/20 0.36
▸ PDE4D Q08499 3/20 0.36
▸ MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31384905 0.99 STAT3 (0.48) STAT3STAT1TP53KDM4ETSHR
SCHEMBL10423762 0.99 STAT3 (0.48) STAT3STAT1TP53KDM4ETSHR
SCHEMBL28250385 0.99 STAT3 (0.48) STAT3STAT1TP53KDM4ETSHR
SCHEMBL28337483 0.99 STAT3 (0.48) STAT3STAT1TP53KDM4ETSHR
SCHEMBL31384871 0.99 STAT3 (0.48) STAT3STAT1TP53KDM4ETSHR
SCHEMBL28275582 0.86 STAT3 (0.46) STAT3STAT1TP53KDM4ETSHR
SCHEMBL226837 0.85 STAT3 (0.59) STAT3STAT1TP53KDM4ETSHR
SCHEMBL6265476 0.84 STAT3 (0.57) STAT3STAT1TP53KDM4ETSHR
SCHEMBL14054511 0.84 STAT3 (0.57) STAT3STAT1TP53KDM4ETSHR
SCHEMBL31499126 0.82 STAT3 (0.52) STAT3STAT1TP53KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5292409-A Electrolytically generating superoxide ion under protective layer of ion exchange material CAPE COD RESEARCH, INC. (US) 1994-03-08 — — US claimed
WO-2025089409-A1 PHOTOELECTRIC CONVERSION ELEMENT, PHOTOELECTRIC CONVERSION DEVICE, MOBILE BODY, AND BUILDING MATERIAL キヤノン株式会社 2025-05-01 — — WO disclosed
WO-2025089384-A1 PHOTOELECTRIC CONVERSION ELEMENT AND PHOTOELECTRIC CONVERSION DEVICE キヤノン株式会社 2025-05-01 — — WO disclosed
WO-2025089411-A1 COMPOSITION, PREPARATION METHOD FOR COMPOSITION, AND PHOTOELECTRIC CONVERSION ELEMENT キヤノン株式会社 2025-05-01 — — WO disclosed
CN-119530876-A Composite catalyst, electrode carrying composite catalyst, and preparation method and application of electrode 中国石油化工股份有限公司 2025-02-28 — — CN disclosed
CN-109301266-A Oxygen reduction catalyst and its preparation method and application 德州新动能铁塔发电有限公司 2019-02-01 — — CN disclosed
CN-107195935-A CIHT dynamical systems 辉光能源公司 2017-09-22 — — CN disclosed
EP-2586091-A1 ELECTRODES AND PRODUCTION AND USE THEREOF BASF SE (DE) 2013-05-01 — — EP disclosed
WO-2011161598-A1 ELECTRODES AND PRODUCTION AND USE THEREOF BASF SE (DE) 2011-12-29 — — WO disclosed
US-20110136774-A1 Anti-Apoptotic Benzodiazepine Receptor Ligand Inhibitors MALFROY-CAMINE BERNARD 2011-06-09 — — US disclosed
US-20100120738-A1 ANTI-APOPTOTIC BENZODIAZEPINE RECEPTOR LIGAND INHIBITORS MALFROY-CAMINE BERNARD 2010-05-13 — — US disclosed
US-20100087534-A1 Use of a Photosensitizing Agent in the Treatment or Prevention of an Inflammation-Associated Disorder in the Gastrointestinal Tract of a Mammal UNIVERSITE DE LAUSANNE (CH) 2010-04-08 — — US disclosed
EP-1926497-A2 USE OF A PHOTOSENSITIZING AGENT IN THE TREATMENT OR PREVENTION OF AN INFLAMMATION-ASSOCIATED DISORDER IN THE GASTROINTESTINAL TRACT OF A MAMMAL Université de Lausanne (CH) 2008-06-04 — — EP disclosed
WO-2008033444-A2 ANTI-APOPTOTIC BENZODIAZEPINE RECEPTOR LIGAND INHIBITORS EUKARION, INC. (US) 2008-03-20 — — WO disclosed
EP-1856751-A2 PRODUCTION OF A PLATINUM-FREE CHELATE CATALYST MATERIAL AS AN INTERMEDIATE PRODUCT, AND FURTHER PROCESSING THEREOF TO OBTAIN AN ELECTROCATALYTIC COATING AS A FINAL PRODUCT Hahn-Meitner-Institut Berlin GmbH (DE) 2007-11-21 — — EP disclosed
WO-2007004045-A9 USE OF A PHOTOSENSITIZING AGENT IN THE TREATMENT OR PREVENTION OF AN INFLAMMATION-ASSOCIATED DISORDER IN THE GASTROINTESTINAL TRACT OF A MAMMAL UNIV LAUSANNE (CH) 2007-05-31 — — WO disclosed
WO-2007004045-A2 USE OF A PHOTOSENSITIZING AGENT IN THE TREATMENT OR PREVENTION OF AN INFLAMMATION-ASSOCIATED DISORDER IN THE GASTROINTESTINAL TRACT OF A MAMMAL UNIVERSITE DE LAUSANNE (CH) 2007-01-11 — — WO disclosed
CN-1279907-C Novel metalloporphyrins and their uses as radiosensitizers for radiation therapy BROOKHAVEN SCIENCE ASS LLC (US) 2006-10-18 — — CN disclosed
WO-2006086979-A2 PRODUCTION OF A PLATINUM-FREE CHELATE CATALYST MATERIAL AS AN INTERMEDIATE PRODUCT, AND FURTHER PROCESSING THEREOF TO OBTAIN AN ELECTROCATALYTIC COATING AS A FINAL PRODUCT HAHN-MEITNER-INSTITUT BERLIN GMBH (DE) 2006-08-24 — — WO disclosed
CN-1620289-A Novel metalloporphyrin compounds and their use as radiosensitizers in radiotherapy BROOKHAVEN SCIENCE ASS LLC (US) 2005-05-25 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100120738-A1 ANTI-APOPTOTIC BENZODIAZEPINE RECEPTOR LIGAND INHIBITORS AIFM1, BAK1, BAX STAT3 2102/4885STAT1 3428/4885TP53 2149/4885
US-20110136774-A1 Anti-Apoptotic Benzodiazepine Receptor Ligand Inhibitors AIFM1, BAK1, BAX STAT3 2102/4885STAT1 3428/4885TP53 2149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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