Milacemide

Milacemide

SCHEMBL194513

CCCCCNCC(N)=O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.63
MAOB P27338 2/20 0.63
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
EPHX1 P07099 6/20 0.46
MEN1 O00255 1/20 0.45
FAAH O00519 1/20 0.45
TP53 P04637 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
SOAT1 P35610 1/20 0.45
KMT2A Q03164 1/20 0.45
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
GAA P10253 1/20 0.44
S1PR2 O95136 5/20 0.44
S1PR4 O95977 5/20 0.44
S1PR1 P21453 5/20 0.44
S1PR3 Q99500 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28278157 0.98 MAOA (0.67) MAOAMAOBALDH1A1TSHREPHX1
SCHEMBL7377007 0.98 MAOA (0.67) MAOAMAOBALDH1A1TSHREPHX1
Milacemide SCHEMBL119651 0.98 MAOA (0.61) MAOAMAOBALDH1A1TSHREPHX1
SCHEMBL7348161 0.98 MAOA (0.67) MAOAMAOBALDH1A1TSHREPHX1
SCHEMBL7344423 0.98 MAOA (0.67) MAOAMAOBALDH1A1TSHREPHX1
SCHEMBL19745716 0.98 MAOA (0.67) MAOAMAOBALDH1A1TSHREPHX1
SCHEMBL7340676 0.98 MAOA (0.67) MAOAMAOBALDH1A1TSHREPHX1
SCHEMBL7339341 0.98 MAOA (0.67) MAOAMAOBALDH1A1TSHREPHX1
SCHEMBL7338476 0.98 MAOA (0.67) MAOAMAOBALDH1A1TSHREPHX1
SCHEMBL28278160 0.98 MAOA (0.67) MAOAMAOBALDH1A1TSHREPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025065271-A1 METHODS AND DEVICES FOR TREATING DEPRESSION Liangzhu Laboratory (CN) 2025-04-03 WO claimed
CN-118894842-A Organic compound, organic photoelectric element containing same and application 上海蓝屏医疗科技有限公司 2024-11-05 CN claimed
CN-118852228-A Organic compound, organic photoelectric element and application thereof 上海蓝屏医疗科技有限公司 2024-10-29 CN claimed
CN-118852227-A Organic compound containing flexible chain, organic photoelectric element containing same and application 上海蓝屏医疗科技有限公司 2024-10-29 CN claimed
US-20230101362-A1 RNA STABILIZATION TEAM MEDICAL LLC 2023-03-30 US claimed
US-10745589-B2 Chemical mechanical polishing (CMP) of cobalt-containing substrate VERSUM MATERIALS US, LLC (US) 2020-08-18 US claimed
US-20200188388-A1 METHODS AND COMPOSITIONS FOR POTENTIATING CNS DRUGS AND REDUCING THEIR SIDE EFFECTS SYNNERVA LTD. (IL) 2020-06-18 US claimed
EP-3562477-A1 METHODS AND COMPOSITIONS FOR POTENTIATING CNS DRUGS AND REDUCING THEIR SIDE EFFECTS Rvx Therapeutics Ltd. (IL) 2019-11-06 EP claimed
CN-110337289-A Methods and compositions for enhancing CNS drugs and reducing their side effects RVX疗法有限公司 2019-10-15 CN claimed
US-20190172720-A1 Chemical Mechanical Polishing (CMP) of Cobalt-Containing Substrate VERSUM MATERIALS US, LLC (US) 2019-06-06 US claimed
EP-0759750-A4 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1998-05-27 EP claimed
WO-1998019674-A2 A METHOD FOR TREATING TENSION-TYPE HEADACHE HEAD EXPLORER APS (DK) 1998-05-14 WO claimed
US-5710155-A NEUROKIN ANTAGONISTS USEFUL IN TREATMENT OF RESPIRATORY, INFLAMMATORY AND GASTROINTESTINAL DISORDERS BOEHRINGER INGELHEIM KG (DE) 1998-01-20 US claimed
WO-1997041878-A1 TREATMENT OF MOOD DISORDERS WITH A GROWTH HORMONE SECRETAGOGUE MERCK & CO., INC. (US) 1997-11-13 WO claimed
EP-0759750-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO, Howard, K. (US) 1997-03-05 EP claimed
EP-0581167-B1 Novel arylglycinamide derivatives and preparative processes therefor and their use for treatment of dysuria KYORIN SEIYAKU KK (JP) 1996-10-09 EP claimed
WO-1995031194-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1995-11-23 WO claimed
US-5439919-A Treatment of urinary incontinence KYORIN PHARMACEUTICAL CO., LTD. (JP) 1995-08-08 US claimed
EP-0581167-A1 Novel arylglycinamide derivatives and preparative processes therefor and their use for treatment of dysuria KYORIN PHARMACEUTICAL CO., LTD. (JP) 1994-02-02 EP claimed
US-4639468-A Derivatives of glycinamide, their preparation and their use CONTINENTAL PHARMA INC. (BE) 1987-01-27 US claimed