Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626044 | 0.96 | STING1 (0.84) | STING1CYP3A4TBK1 | |
| SCHEMBL19451509 | 0.96 | STING1 (0.84) | STING1CYP3A4TBK1 | |
| SCHEMBL29586400 | 0.96 | STING1 (0.84) | STING1CYP3A4TBK1 | |
| SCHEMBL28413370 | 0.96 | STING1 (0.84) | STING1CYP3A4TBK1 | |
| SCHEMBL22150065 | 0.94 | STING1 (0.76) | STING1CYP3A4TBK1 | |
| SCHEMBL25074339 | 0.93 | STING1 (0.80) | STING1CYP3A4TBK1 | |
| SCHEMBL22150401 | 0.93 | STING1 (0.76) | STING1CYP3A4 | |
| SCHEMBL20066424 | 0.93 | STING1 (0.69) | STING1CYP3A4TBK1 | |
| SCHEMBL20066383 | 0.93 | STING1 (0.81) | STING1CYP3A4TBK1 | |
| SCHEMBL23227988 | 0.92 | STING1 (0.78) | STING1CYP3A4TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017175147-A1 | HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-10-12 | — | — | WO | disclosed |