SCHEMBL29626044

SCHEMBL29626044

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)ccc2n1C/C=C/Cn1c(NC(=O)c2cc(C)nn2CC)nc2cc(C(N)=O)cc(OCCCO)c21

nearest known ligand 0.84

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.84
▸ CYP3A4 P08684 1/20 0.67
▸ TBK1 Q9UHD2 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19451509 1.00 STING1 (0.84) STING1CYP3A4TBK1
SCHEMBL28413370 1.00 STING1 (0.84) STING1CYP3A4TBK1
SCHEMBL29586400 1.00 STING1 (0.84) STING1CYP3A4TBK1
SCHEMBL25074339 0.97 STING1 (0.80) STING1CYP3A4TBK1
SCHEMBL20066383 0.96 STING1 (0.81) STING1CYP3A4TBK1
SCHEMBL23227988 0.96 STING1 (0.78) STING1CYP3A4TBK1
SCHEMBL19451711 0.96 STING1 (0.78) STING1CYP3A4TBK1
SCHEMBL19451513 0.96 STING1 (0.80) STING1CYP3A4TBK1
SCHEMBL20066425 0.95 STING1 (0.75) STING1CYP3A4TBK1
SCHEMBL20066435 0.94 STING1 (0.75) STING1CYP3A4TBK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4346894-A1 ADJUVANTS GlaxoSmithKline Biologicals S.A. (BE) 2024-04-10 — — EP claimed
WO-2022248353-A1 ADJUVANTS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-12-01 — — WO claimed
WO-2025029832-A2 STING AGONIST COMPOUNDS AND CONJUGATES SUTRO BIOPHARMA, INC. (US) 2025-02-06 — — WO disclosed
EP-4419100-A1 ADJUVANT COMPOSITION COMPRISING STING AGONISTS GlaxoSmithKline Biologicals S.A. (BE) 2024-08-28 — — EP disclosed
CN-118215475-A Adjuvant compositions comprising STING agonists 葛兰素史克生物有限公司 2024-06-18 — — CN disclosed
EP-4346894-A1 ADJUVANTS GlaxoSmithKline Biologicals S.A. (BE) 2024-04-10 — — EP disclosed
WO-2023066872-A1 ADJUVANT COMPOSITION COMPRISING STING AGONISTS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-04-27 — — WO disclosed
WO-2023020992-A1 NOVEL METHODS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-02-23 — — WO disclosed
WO-2023020994-A1 NOVEL METHODS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-02-23 — — WO disclosed
WO-2023020993-A1 NOVEL METHODS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-02-23 — — WO disclosed
WO-2022248353-A1 ADJUVANTS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-12-01 — — WO disclosed
EP-4032885-A1 HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS GlaxoSmithKline Intellectual Property Development Limited (GB) 2022-07-27 — — EP disclosed
EP-3440076-B1 HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS GLAXOSMITHKLINE IP DEV LTD (GB) 2022-06-01 — — EP disclosed
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