Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL970792 | 1.00 | — | — | |
| Bromide SCHEMBL7119680 | 1.00 | — | — | |
| Bromide SCHEMBL1403762 | 1.00 | — | — | |
| Bromide SCHEMBL9345034 | 1.00 | — | — | |
| Bromide SCHEMBL7434275 | 1.00 | — | — | |
| Bromide SCHEMBL7402625 | 1.00 | CA1 (0.50) | — | |
| Bromide SCHEMBL11273331 | 1.00 | — | — | |
| Bromide SCHEMBL4237775 | 1.00 | — | — | |
| Bromide SCHEMBL8143980 | 1.00 | — | — | |
| Bromide SCHEMBL2303098 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222336-A1 | SINGLE ENANTIOMER BETA-AGONISTS, METHODS FOR THE PRODUCTION THEREOF AND THE USE THEREOF AS MEDICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | US | claimed |
| EP-4077325-B1 | SELECTIVE CDK4/6 INHIBITOR CANCER THERAPEUTICS | LUNELLA BIOTECH INC (CA) | 2026-03-11 | — | — | EP | disclosed |
| US-20250304591-A1 | SUBSTITUTED PYRROLO[2,3-d]PYRIMIDINES AS SELECTIVE CDK 4/6 INHIBITORS | LUNELLA BIOTECH INC (CA) | 2025-10-02 | — | — | US | disclosed |
| US-12358920-B2 | Substituted pyrrolo[2,3-d]pyrimidines as selective CDK 4/6 inhibitors | LUNELLA BIOTECH, INC. (CA) | 2025-07-15 | — | — | US | disclosed |
| US-12319690-B2 | Selective CDK 4/6 inhibitor cancer therapeutics | LUNELLA BIOTECH, INC. (CA) | 2025-06-03 | — | — | US | disclosed |
| CN-114901666-B | Selective CDK4/6 inhibitor type cancer therapeutic drug | 卢内拉生物技术有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-118652252-A | Selective CDK4/6 inhibitor type cancer therapeutic drug | 卢内拉生物技术有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-115023424-B | Selective CDK4/6 inhibitor type cancer therapeutic drug | 卢内拉生物技术有限公司 | 2024-07-02 | — | — | CN | disclosed |
| EP-4385948-A1 | GRAPHENE GRID, METHOD FOR PRODUCING GRAPHENE GRID, AND METHOD FOR ANALYZING STRUCTURE OF STRUCTURAL ANALYSIS TARGET SUBSTANCE | OSAKA UNIVERSITY (JP) | 2024-06-19 | — | — | EP | disclosed |
| US-12012426-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2024-06-18 | — | — | US | disclosed |
| US-8309573-B2 | Salt of isoquinoline compound and crystal thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-11-13 | — | — | US | disclosed |
| US-20110130419-A1 | NOVEL SALT OF ISOQUINOLINE COMPOUND AND CRYSTAL THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-06-02 | — | — | US | disclosed |
| EP-2184282-A1 | NOVEL SALT OF ISOQUINOLINE COMPOUND AND CRYSTAL THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-05-12 | — | — | EP | disclosed |
| WO-2005118715-A2 | GAS GENERANT AND SYNTHESIS | AUTOMOTIVE SYSTEMS LABORATORY, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| EP-0803766-A1 | Photothermographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1997-10-29 | — | — | EP | disclosed |
| EP-0371564-A2 | (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-06-06 | — | — | EP | disclosed |
| US-4562063-A | ZINC COMPOUND | COLGATE-PALMOLIVE COMPANY (US) | 1985-12-31 | — | — | US | disclosed |
| US-4562065-A | LIQUID VEHICLE COMPRISING WATER, GELLING AGENT, POLISHING AGENT AND SYNTHETIC AMORPHOUS SILICA GEL | COLGATE-PALMOLIVE COMPANY (US) | 1985-12-31 | — | — | US | disclosed |
| US-4562066-A | CONTAINING WATER WITH GELLING AND POLISHING AGENT | COLGATE-PALMOLIVE COMPANY (US) | 1985-12-31 | — | — | US | disclosed |
| US-3994901-A | BETA-ADRENO-RECEPTOR STIMULANTS | OTSUKA PHARMACEUTICAL COMPANY LIMITED (JA) | 1976-11-30 | — | — | US | disclosed |