Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7119680 | 1.00 | — | — | |
| Bromide SCHEMBL1945233 | 1.00 | — | — | |
| Bromide SCHEMBL1403762 | 1.00 | — | — | |
| Bromide SCHEMBL9345034 | 1.00 | — | — | |
| Bromide SCHEMBL7434275 | 1.00 | — | — | |
| Bromide SCHEMBL7402625 | 1.00 | CA1 (0.50) | — | |
| Bromide SCHEMBL11273331 | 1.00 | — | — | |
| Bromide SCHEMBL4237775 | 1.00 | — | — | |
| Bromide SCHEMBL8143980 | 1.00 | — | — | |
| Bromide SCHEMBL2303098 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961751-B1 | ACID ADDITION SALT OF OPTICALLY ACTIVE DIHYDROPYRIDINE DERIVATIVE | UBE INDUSTRIES (JP) | 2012-11-21 | — | — | EP | claimed |
| JP-61215396-A | — | — | None | — | — | JP | disclosed |
| US-20230272449-A1 | IDENTIFICATION OF INHIBITORS OF TCPC AND TIR NADase ACTIVITY | WASHINGTON UNIVERSITY | 2023-08-31 | — | — | US | disclosed |
| US-20200283820-A1 | IDENTIFICATION OF INHIBITORS OF TCPC AND TIR NADase ACTIVITY | WASHINGTON UNIVERSITY | 2020-09-10 | — | — | US | disclosed |
| US-20190298841-A1 | Nucleic Acid Complexes | PROCARTA BIOSYSTEMS LTD (GB) | 2019-10-03 | — | — | US | disclosed |
| CN-110300624-A | Cupric MOZ zeolite for selective N Ox reduction catalysts | 优美科股份公司及两合公司 | 2019-10-01 | — | — | CN | disclosed |
| US-10350299-B2 | Nucleic acid complexes | PROCARTA BIOSYSTEMS LTD. (GB) | 2019-07-16 | — | — | US | disclosed |
| WO-2019067625-A1 | IDENTIFICATION OF INHIBITORS OF TCPC AND TIR NADASE ACTIVITY | WASHINGTON UNIVERSITY (US) | 2019-04-04 | — | — | WO | disclosed |
| CN-105705610-B | Compound with end heteroaryl cyano group ethenylidene and its application in organic solar batteries | 巴斯夫欧洲公司 | 2018-01-30 | — | — | CN | disclosed |
| US-20170340745-A1 | NUCLEIC ACID COMPLEXES | PROCARTA BIOSYSTEMS LTD. (GB) | 2017-11-30 | — | — | US | disclosed |
| US-20100305326-A1 | Chemical Fragment Screening and Assembly Utilizing Common Chemistry for NMR Probe Introduction and Fragment Linkage | MARQUETTE UNIVERSITY (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100304998-A1 | Chemical Proteomic Assay for Optimizing Drug Binding to Target Proteins | MARQUETTE UNIVERSITY (US) | 2010-12-02 | — | — | US | disclosed |
| EP-1674444-A1 | METHOD FOR PRODUCING ESTER CONDENSED PRODUCT | Japan Science and Technology Agency (JP) | 2006-06-28 | — | — | EP | disclosed |
| WO-1997048705-A1 | POTASSIUM CHANNEL BLOCKERS | UNIVERSITY COLLEGE LONDON (GB) | 1997-12-24 | — | — | WO | disclosed |
| EP-0543001-A1 | USE OF ANTIARRHYTHMIC AGENTS TO LOWER CHOLESTEROL | THE UNIVERSITY OF ROCHESTER (US) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992022299-A2 | USE OF ANTIARRHYTHMIC AGENTS TO LOWER CHOLESTEROL | UNIVERSITY OF ROCHESTER (US) | 1992-12-23 | — | — | WO | disclosed |
| US-5166142-A | Anticholesterol agents such as quinidine, procainamide or disopyramide | UNIVERSITY OF ROCHESTER (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0188361-B1 | AMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1991-03-06 | — | — | EP | disclosed |
| JP-S61215396-A | 7-AMINO-3-PYRIDINIUM METHYL-CEPHEM DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1986-09-25 | — | — | JP | disclosed |
| US-4238611-A | Polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepine | SPOFA, UNITED PHARMACEUTICAL WORKS (CS) | 1980-12-09 | — | — | US | disclosed |