Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | BRD4 | O60885 | 7/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456128 | 0.83 | BRD4 (0.42) | ITGB3ITGA2BBRD4ROCK2 | |
| SCHEMBL21649797 | 0.83 | BRD4 (0.43) | BRD4 | |
| SCHEMBL19456310 | 0.82 | BRD4 (0.49) | BRD4MAPK14 | |
| SCHEMBL19456189 | 0.82 | MAPT (0.41) | BRD4MAPK14 | |
| SCHEMBL19456152 | 0.81 | BRD4 (0.50) | BRD4 | |
| SCHEMBL19456175 | 0.79 | BRD4 (0.46) | BRD4 | |
| SCHEMBL19456350 | 0.79 | BRD4 (0.41) | BRD4LCKKITSRCMAPK14 | |
| SCHEMBL19456093 | 0.79 | BRD4 (0.39) | BRD4 | |
| SCHEMBL19456090 | 0.77 | BRD4 (0.36) | BRD4 | |
| SCHEMBL19456134 | 0.75 | BRD4 (0.66) | ITGB3ITGA2BBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017174620-A1 | BENZO[B]FURANS AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-10-12 | — | — | WO | disclosed |