Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 19/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.49 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456719 | 0.89 | SLC22A12 (0.63) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL19456721 | 0.82 | SLC22A12 (0.53) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL19456723 | 0.81 | SLC22A12 (0.48) | SLC22A12SLC22A6SLC22A11ABCG2NSD2 | |
| SCHEMBL15165680 | 0.78 | SLC22A12 (0.78) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL19456716 | 0.74 | SLC22A12 (0.54) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL18979067 | 0.72 | SLC22A12 (0.59) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL19456722 | 0.70 | SLC22A12 (0.60) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL28399999 | 0.70 | SLC22A12 (0.42) | SLC22A12 | |
| SCHEMBL17899844 | 0.69 | SLC22A12 (0.47) | SLC22A12 | |
| SCHEMBL19456817 | 0.69 | SLC22A12 (0.43) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017173965-A1 | NOVEL URAT1 INHIBITOR AND PHARMACEUTICAL APPLICATION THEREOF | 江苏新元素医药科技有限公司 | 2017-10-12 | — | — | WO | disclosed |