Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456819 | 0.87 | SLC22A12 (0.56) | SLC22A12 | |
| SCHEMBL19456710 | 0.83 | SSTR4 (0.42) | SLC22A12PLCG1L3MBTL1 | |
| SCHEMBL19456912 | 0.83 | SLC22A12 (0.53) | SLC22A12PLCG1 | |
| SCHEMBL19456737 | 0.81 | SLC22A12 (0.36) | SLC22A12PLCG1L3MBTL1 | |
| SCHEMBL19456735 | 0.80 | SLC22A12 (0.35) | SLC22A12PLCG1 | |
| SCHEMBL19456820 | 0.79 | SLC22A12 (0.53) | SLC22A12PLCG1TGFBR1 | |
| SCHEMBL19456917 | 0.77 | PLCG1 (0.36) | SLC22A12PLCG1 | |
| SCHEMBL19456910 | 0.74 | SLC22A12 (0.79) | SLC22A12PLCG1TGFBR1 | |
| SCHEMBL28399999 | 0.74 | SLC22A12 (0.42) | SLC22A12PLCG1KMT2AL3MBTL1ELANE | |
| SCHEMBL19456704 | 0.70 | MALT1 (0.35) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107683282-B | URAT1 inhibitor and application thereof in medicine | 江苏新元素医药科技有限公司 | 2020-05-22 | — | — | CN | disclosed |
| WO-2017173965-A1 | NOVEL URAT1 INHIBITOR AND PHARMACEUTICAL APPLICATION THEREOF | 江苏新元素医药科技有限公司 | 2017-10-12 | — | — | WO | disclosed |