SCHEMBL19456804

SCHEMBL19456804

CSc1sc(N(C)C(=O)Cc2ccc(-c3cc(F)ccc3P)cc2)nc1C

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA12 O43570 19/20 0.59
CA1 P00915 19/20 0.59
CA2 P00918 19/20 0.59
CA5A P35218 19/20 0.59
CA9 Q16790 19/20 0.59
CA5B Q9Y2D0 19/20 0.59
WNT3A P56704 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19456805 0.90 CA12 (0.72) CA12CA1CA2CA5ACA9
SCHEMBL29635263 0.84 CA12 (0.66) CA12CA1CA2CA5ACA9
SCHEMBL22294749 0.83 CA12 (0.72) CA12CA1CA2CA5ACA9
SCHEMBL22055974 0.83 CA12 (0.75) CA12CA1CA2CA5ACA9
SCHEMBL25892626 0.81 CA12 (0.53) CA12CA1CA2CA5ACA9
SCHEMBL24767087 0.80 CA12 (0.62) CA12CA1CA2CA5ACA9
SCHEMBL24766901 0.79 CA12 (0.66) CA12CA1CA2CA5ACA9
SCHEMBL25893742 0.79 CA12 (0.61) CA12CA1CA2CA5ACA9
SCHEMBL25854795 0.79 CA12 (0.61) CA12CA1CA2CA5ACA9
SCHEMBL24767096 0.77 CA12 (0.74) CA12CA1CA2CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017174640-A1 AMINOTHIAZOLE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS INNOVATIVES MOLECULES GMBH (DE) 2017-10-12 WO disclosed