SCHEMBL29635263

SCHEMBL29635263

[2H]C([2H])([2H])c1nc(N(C)C(=O)Cc2ccc(-c3cc(F)ccc3F)cc2)sc1SC

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA12 O43570 18/20 0.66
CA1 P00915 18/20 0.66
CA2 P00918 18/20 0.66
CA5A P35218 18/20 0.66
CA9 Q16790 18/20 0.66
CA5B Q9Y2D0 18/20 0.66
WNT3A P56704 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19456805 0.93 CA12 (0.72) CA12CA1CA2CA5ACA9
SCHEMBL24767087 0.87 CA12 (0.62) CA12CA1CA2CA5ACA9
SCHEMBL22294749 0.86 CA12 (0.72) CA12CA1CA2CA5ACA9
SCHEMBL22055974 0.86 CA12 (0.75) CA12CA1CA2CA5ACA9
SCHEMBL25893742 0.85 CA12 (0.61) CA12CA1CA2CA5ACA9
SCHEMBL25854795 0.85 CA12 (0.61) CA12CA1CA2CA5ACA9
SCHEMBL29635265 0.84 CA12 (0.88) CA12CA1CA2CA5ACA9
SCHEMBL19456804 0.84 CA12 (0.59) CA12CA1CA2CA5ACA9
SCHEMBL29635239 0.84 CA12 (0.66) CA12CA1CA2CA5ACA9
SCHEMBL29635247 0.83 CA12 (0.73) CA12CA1CA2CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250115565-A1 SOLID CRYSTALLINE FORMS OF HELICASE-PRIMASE INHIBITORS AND PROCESS OF PREPARATION THEREOF INNOVATIVE MOLECULES GMBH (DE) 2025-04-10 US disclosed
CN-118556045-A Solid crystalline forms of a helicase-primase inhibitor and methods of making the same 创新分子股份有限公司 2024-08-27 CN disclosed
EP-4237414-A1 DEUTERATED AMINOTHIAZOLE COMPOUNDS AS ANTIVIRAL COMPOUNDS Innovative Molecules GmbH (DE) 2023-09-06 EP disclosed
WO-2022090409-A1 DEUTERATED AMINOTHIAZOLE COMPOUNDS AS ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2022-05-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115565-A1 SOLID CRYSTALLINE FORMS OF HELICASE-PRIMASE INHIBITORS AND PROCESS OF PREPARATION THEREOF DNA2, RECQL, BLM CA12 3081/4885CA1 1807/4885CA2 2800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.