Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.79 |
| ▸ | KDM1A | O60341 | 4/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18105594 | 0.89 | SLC22A12 (0.75) | SLC22A12KDM1AEGLN2GAA | |
| SCHEMBL19961093 | 0.89 | SLC22A12 (0.84) | SLC22A12KDM1AEGLN2GAA | |
| SCHEMBL18105516 | 0.89 | SLC22A12 (1.00) | SLC22A12 | |
| SCHEMBL19456820 | 0.83 | SLC22A12 (0.53) | SLC22A12PLCG1TGFBR1 | |
| SCHEMBL19456912 | 0.82 | SLC22A12 (0.53) | SLC22A12KDM1APLCG1EGLN2 | |
| SCHEMBL19967246 | 0.74 | SLC22A12 (0.62) | SLC22A12KDM1AEGLN2GAA | |
| SCHEMBL19456817 | 0.74 | SLC22A12 (0.43) | SLC22A12PLCG1TGFBR1 | |
| SCHEMBL15463510 | 0.72 | SLC22A12 (0.77) | SLC22A12 | |
| SCHEMBL15030116 | 0.71 | SLC22A12 (0.52) | SLC22A12PLCG1 | |
| SCHEMBL19456815 | 0.70 | SLC22A12 (0.69) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017173965-A1 | NOVEL URAT1 INHIBITOR AND PHARMACEUTICAL APPLICATION THEREOF | 江苏新元素医药科技有限公司 | 2017-10-12 | — | — | WO | disclosed |