Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456916 | 0.87 | SLC22A12 (0.42) | SLC22A12 | |
| SCHEMBL19456915 | 0.84 | SLC22A12 (0.31) | SLC22A12 | |
| SCHEMBL19456817 | 0.77 | SLC22A12 (0.43) | PLCG1SLC22A12 | |
| SCHEMBL19456713 | 0.70 | SLC22A12 (0.33) | SLC22A12 | |
| SCHEMBL19456912 | 0.66 | SLC22A12 (0.53) | PLCG1SLC22A12 | |
| SCHEMBL19456820 | 0.66 | SLC22A12 (0.53) | PLCG1SLC22A12 | |
| SCHEMBL19456710 | 0.65 | SSTR4 (0.42) | PLCG1SLC22A12 | |
| SCHEMBL15159024 | 0.64 | SLC22A12 (0.48) | SLC22A12 | |
| SCHEMBL19456731 | 0.64 | RIPK2 (0.36) | — | |
| SCHEMBL19456819 | 0.64 | SLC22A12 (0.56) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107683282-B | URAT1 inhibitor and application thereof in medicine | 江苏新元素医药科技有限公司 | 2020-05-22 | — | — | CN | disclosed |
| WO-2017173965-A1 | NOVEL URAT1 INHIBITOR AND PHARMACEUTICAL APPLICATION THEREOF | 江苏新元素医药科技有限公司 | 2017-10-12 | — | — | WO | disclosed |