Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10542566 | 0.84 | PTGS1 (0.46) | PTGS1PTGS2HDAC1HDAC2RAB9A | |
| SCHEMBL27899681 | 0.80 | PTGS1 (0.47) | PTGS1PTGS2HDAC1HDAC2RAB9A | |
| SCHEMBL18851551 | 0.77 | HDAC1 (0.49) | PTGS1PTGS2HDAC1HDAC2RAB9A | |
| SCHEMBL871327 | 0.77 | PTGS1 (0.51) | PTGS1PTGS2HDAC1HDAC2RAB9A | |
| SCHEMBL9605459 | 0.72 | HDAC1 (0.48) | PTGS1PTGS2HDAC1HDAC2RAB9A | |
| SCHEMBL2079932 | 0.71 | PTGS1 (0.58) | PTGS1PTGS2RAB9ANPC1KDM4E | |
| SCHEMBL7929884 | 0.70 | PTGS1 (0.72) | PTGS1PTGS2RAB9ANPC1KDM4E | |
| SCHEMBL29373950 | 0.70 | PTGS1 (0.62) | PTGS1PTGS2RAB9ANPC1KDM4E | |
| SCHEMBL171008 | 0.70 | PTGS1 (0.52) | PTGS1PTGS2RAB9ANPC1KDM4E | |
| SCHEMBL31731985 | 0.69 | RAB9A (0.67) | PTGS1PTGS2RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017176040-A1 | HETEROCYCLIC COMPOUND DECOMPOSING RAS AND USES THEREOF | 연세대학교 산학협력단 | 2017-10-12 | — | — | WO | disclosed |