Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 14/20 | 0.44 |
| ▸ | CDK9 | P50750 | 5/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1946413 | 1.00 | CCNT1 (0.44) | CCNT1CDK9CCNKABL1IDH1 | |
| SCHEMBL1463037 | 1.00 | CCNT1 (0.44) | CCNT1CDK9CCNKABL1IDH1 | |
| SCHEMBL1461835 | 0.88 | CCNT1 (0.44) | CCNT1CDK9ABL1CSF1R | |
| SCHEMBL1947637 | 0.88 | CCNT1 (0.44) | CCNT1CDK9ABL1CSF1R | |
| SCHEMBL1947509 | 0.88 | CCNT1 (0.44) | CCNT1CDK9ABL1CSF1R | |
| SCHEMBL1192562 | 0.79 | CCNT1 (0.68) | CCNT1CDK9CCNK | |
| SCHEMBL1464131 | 0.77 | CCNT1 (0.46) | CCNT1CDK9PIK3CACSF1RMAPK1 | |
| SCHEMBL1463040 | 0.77 | CCNT1 (0.55) | CCNT1CDK9CCNK | |
| SCHEMBL1461871 | 0.74 | CSF1R (0.36) | IDH1PIP5K1CCSF1RMAPK1 | |
| SCHEMBL1461873 | 0.74 | CSF1R (0.36) | IDH1PIP5K1CCSF1RMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012101063-A1 | N-ACYL PYRIDINE BIARYL COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2012-08-02 | — | — | WO | disclosed |
| WO-2012101064-A1 | N-ACYL PYRIMIDINE BIARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-08-02 | — | — | WO | disclosed |
| US-20110130380-A1 | Heteroaryl Kinase Inhibitors | NOVARTIS AG (CH) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130380-A1 | Heteroaryl Kinase Inhibitors | CDK2, CDK1, CDKL1 | CCNT1 47/4885CDK9 5/4885CCNK 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.