Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 18/20 | 0.55 |
| ▸ | CDK9 | P50750 | 4/20 | 0.51 |
| ▸ | CCNK | O75909 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1192562 | 0.89 | CCNT1 (0.68) | CCNT1CDK9CCNK | |
| SCHEMBL1461836 | 0.88 | CCNT1 (0.55) | CCNT1CDK9CCNK | |
| SCHEMBL1191988 | 0.82 | CCNT1 (0.59) | CCNT1CDK9CCNK | |
| SCHEMBL1192708 | 0.81 | CCNT1 (0.63) | CCNT1CDK9CCNK | |
| SCHEMBL1192303 | 0.80 | CDK9 (0.57) | CCNT1CDK9CCNK | |
| SCHEMBL12874296 | 0.80 | CDK9 (0.57) | CCNT1CDK9CCNK | |
| SCHEMBL12565784 | 0.78 | CCNT1 (0.52) | CCNT1CDK9CCNK | |
| SCHEMBL1192372 | 0.78 | CCNK (0.61) | CCNT1CDK9CCNK | |
| SCHEMBL1191677 | 0.77 | CCNT1 (0.57) | CCNT1CDK9CCNK | |
| SCHEMBL1463037 | 0.77 | CCNT1 (0.44) | CCNT1CDK9CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473499-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Novartis AG (CH) | 2012-07-11 | — | — | EP | disclosed |
| WO-2011026911-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2011-03-10 | — | — | WO | disclosed |