Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 11/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19765270 | 1.00 | CDC25A (0.35) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL19765265 | 0.96 | CES1 (0.33) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL13058822 | 0.85 | NR1H2 (0.33) | ALDH1A1HPGDKMT2A | |
| SCHEMBL16668598 | 0.85 | NR1H2 (0.33) | ALDH1A1HPGDKMT2A | |
| SCHEMBL16668594 | 0.85 | NR1H2 (0.33) | ALDH1A1HPGDKMT2A | |
| SCHEMBL15301265 | 0.83 | CES1 (0.34) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL15827138 | 0.81 | KDM4E (0.36) | ALDH1A1HPGDKMT2A | |
| SCHEMBL16668725 | 0.81 | NR1H2 (0.30) | — | |
| SCHEMBL16674418 | 0.81 | NR1H2 (0.30) | — | |
| SCHEMBL19765273 | 0.81 | CDC25A (0.37) | CDC25ACES1ALDH1A1ALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10263190-B2 | Difluorobithiophene-based donor-acceptor polymers for electronic and photonic applications | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-04-16 | — | — | US | disclosed |
| US-20170301862-A1 | Difluorobithiophene-Based Donor-Acceptor Polymers for Electronic and Photonic Applications | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-10-19 | — | — | US | disclosed |
| US-20170301862-A1 | Difluorobithiophene-Based Donor-Acceptor Polymers for Electronic and Photonic Applications | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170301862-A1 | Difluorobithiophene-Based Donor-Acceptor Polymers for Electronic and Photonic Applications | GFPT1, FDFT1, DIMT1 | CDC25A 2701/4885CES1 3444/4885ALDH1A1 1167/4885 |
| US-10263190-B2 | Difluorobithiophene-based donor-acceptor polymers for electronic and photonic applications | GFPT1, FDFT1, DIMT1 | CDC25A 2701/4885CES1 3444/4885ALDH1A1 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.