Flumioxazin

Flumioxazin

SCHEMBL19463115

C#CCN1C(=O)COc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21.C[n+]1ccc(-c2cc[n+](C)cc2)cc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 1/20 0.36
GRM7 Q14831 1/20 0.36
GRM4 Q14833 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flumioxazin SCHEMBL39699 0.90 GRM1 (0.37) GRM1GRM7GRM4
Flumioxazin SCHEMBL29539500 0.90 GRM1 (0.37) GRM1GRM7GRM4
Flumioxazin SCHEMBL29088353 0.89 GRM1 (0.37) GRM1GRM7GRM4
Flumioxazin SCHEMBL19641848 0.88 GRM1 (0.39) GRM1GRM7GRM4
Flumioxazin SCHEMBL19462956 0.84
Flumioxazin SCHEMBL7584944 0.83
Flumioxazin SCHEMBL2231264 0.83
Flumioxazin SCHEMBL28240390 0.80 GRM7 (0.37) GRM1GRM7GRM4
SCHEMBL10374243 0.80 GRM7 (0.37) GRM1GRM7GRM4
Flumioxazin SCHEMBL7580601 0.80 GRM7 (0.35) GRM1GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3442962-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS Syngenta Participations AG (CH) 2019-02-20 EP disclosed
WO-2017178582-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2017-10-19 WO disclosed