Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396197 | 0.91 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1CA1 | |
| SCHEMBL66269 | 0.91 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1CA1 | |
| SCHEMBL30013512 | 0.91 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1CA1 | |
| SCHEMBL21462144 | 0.90 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1CA1 | |
| Metsulfuron-Methyl SCHEMBL9451064 | 0.88 | NPC1 (0.46) | MAPTALDH1A1KDM4ENPC1CA1 | |
| Chlorsulfuron SCHEMBL3428108 | 0.86 | ALDH1A1 (0.55) | MAPTALDH1A1KDM4ENPC1CA1 | |
| SCHEMBL7452390 | 0.85 | MAPT (0.49) | MAPTALDH1A1KDM4ENPC1CA1 | |
| Diquat SCHEMBL19463478 | 0.85 | MAPT (0.39) | MAPTALDH1A1KDM4ENPC1CA1 | |
| SCHEMBL10839581 | 0.84 | MAPT (0.44) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 | |
| Iodosulfuron SCHEMBL19463106 | 0.83 | MAPT (0.41) | MAPTALDH1A1KDM4ENPC1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442962-A1 | HERBICIDAL PYRIDAZINONE COMPOUNDS | Syngenta Participations AG (CH) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017178582-A1 | HERBICIDAL PYRIDAZINONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-19 | — | — | WO | disclosed |