Oxadiazon

Oxadiazon

SCHEMBL19463584

CC(C)Oc1cc(-n2nc(C(C)(C)C)oc2=O)c(Cl)cc1Cl.C[n+]1ccc(-c2cc[n+](C)cc2)cc1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPOX P50336 14/20 0.80
MEN1 O00255 3/20 0.80
KMT2A Q03164 3/20 0.80
TDP1 Q9NUW8 2/20 0.80
NR1I2 O75469 1/20 0.80
HPGD P15428 2/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 2/20 0.37
HTT P42858 1/20 0.37
RECQL P46063 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxadiazon SCHEMBL38813 0.90 PPOX (1.00) PPOXMEN1KMT2ATDP1NR1I2
Oxadiazon SCHEMBL29423792 0.90 PPOX (1.00) PPOXMEN1KMT2ATDP1NR1I2
Oxadiazon SCHEMBL1068568 0.90 PPOX (1.00) PPOXMEN1KMT2ATDP1NR1I2
Oxadiazon SCHEMBL21633846 0.89 PPOX (0.98) PPOXMEN1KMT2ATDP1NR1I2
Oxadiazon SCHEMBL27741702 0.89 PPOX (0.98) PPOXMEN1KMT2ATDP1NR1I2
Oxadiazon SCHEMBL27754194 0.85 PPOX (0.89) PPOXMEN1KMT2ATDP1NR1I2
Oxadiazon SCHEMBL27877800 0.83 PPOX (0.85) PPOXMEN1KMT2ATDP1NR1I2
Oxadiazon SCHEMBL19462953 0.82 PPOX (0.73) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL10553808 0.82 PPOX (0.81) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL10551436 0.82 PPOX (0.81) PPOXMEN1KMT2ATDP1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3442962-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS Syngenta Participations AG (CH) 2019-02-20 EP disclosed
WO-2017178582-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2017-10-19 WO disclosed