Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 20/20 | 0.64 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
| ▸ | TGM1 | P22735 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19463812 | 1.00 | TGM2 (0.64) | TGM2F13A1TGM1 | |
| SCHEMBL19463639 | 0.90 | TGM2 (0.65) | TGM2F13A1TGM1 | |
| SCHEMBL19463905 | 0.84 | TGM2 (0.71) | TGM2 | |
| SCHEMBL19463907 | 0.84 | TGM2 (0.71) | TGM2 | |
| SCHEMBL19464178 | 0.83 | TGM2 (0.65) | TGM2 | |
| SCHEMBL19464177 | 0.83 | TGM2 (0.65) | TGM2 | |
| SCHEMBL19463278 | 0.82 | TGM2 (0.67) | TGM2 | |
| SCHEMBL19463277 | 0.82 | TGM2 (0.67) | TGM2 | |
| SCHEMBL19463817 | 0.78 | TGM2 (1.00) | TGM2F13A1TGM1 | |
| SCHEMBL22895148 | 0.78 | TGM2 (1.00) | TGM2F13A1TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442533-A1 | TG2 INHIBITOR COMPOUNDS AND USES THEREOF | University Of Ottawa (CA) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017179018-A1 | TG2 INHIBITOR COMPOUNDS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2017-10-19 | — | — | WO | disclosed |