Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.49 |
| ▸ | TUBB | P07437 | 3/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625442 | 0.84 | TUBB1 (0.58) | ALDH1A1TUBB1MEN1KMT2AKDM4E | |
| SCHEMBL8590728 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HPGDTUBB1MEN1KMT2A | |
| SCHEMBL4143482 | 0.81 | ALDH1A1 (0.77) | ALDH1A1HPGDMEN1KMT2AMAPK1 | |
| SCHEMBL31679677 | 0.81 | TUBB1 (0.54) | ALDH1A1HPGDTUBB1MEN1KMT2A | |
| SCHEMBL20079471 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TUBB1MEN1KMT2AKDM4E | |
| SCHEMBL23734449 | 0.79 | TUBB1 (0.55) | ALDH1A1TUBB1MEN1KMT2AKDM4E | |
| SCHEMBL907576 | 0.79 | TPMT (0.56) | ALDH1A1HPGDTUBB1MEN1KMT2A | |
| SCHEMBL23734331 | 0.78 | TUBB1 (0.49) | ALDH1A1HPGDTUBB1MEN1KMT2A | |
| SCHEMBL6160353 | 0.77 | TUBB1 (0.54) | ALDH1A1HPGDTUBB1MEN1KMT2A | |
| SCHEMBL10789120 | 0.77 | TSHR (0.56) | TUBB1MEN1KMT2ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790197-B2 | Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient | KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R & D (BE) | 2017-10-17 | — | — | US | disclosed |