⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21533953 | 0.75 | — | — | |
| SCHEMBL611663 | 0.72 | POLB (0.35) | — | |
| SCHEMBL25666129 | 0.71 | HRH3 (0.31) | — | |
| SCHEMBL21325017 | 0.70 | DPP4 (0.36) | — | |
| SCHEMBL21690604 | 0.68 | — | — | |
| SCHEMBL25136544 | 0.64 | POLB (0.33) | — | |
| SCHEMBL17035447 | 0.64 | POLB (0.33) | — | |
| SCHEMBL19543655 | 0.63 | POLB (0.31) | — | |
| SCHEMBL19443026 | 0.63 | POLB (0.31) | — | |
| SCHEMBL24926077 | 0.61 | PIK3CD (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685738-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | OCUTERRA THERAPEUTICS, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-20230129394-A1 | METHODS OF TREATING OR PREVENTING VIRAL INFECTION WITH FLUORINATED AlphaV INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20210277000-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FELIQS CORPORATION (JP) | 2021-09-09 | — | — | US | disclosed |
| US-20190225609-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FELIQS CORPORATION (JP) | 2019-07-25 | — | — | US | disclosed |
| US-10301307-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | SCIFLUOR LIFE SCIENCES, INC. (US) | 2019-05-28 | — | — | US | disclosed |
| US-20190040073-A1 | NONANOIC AND DECANOIC ACID DERIVATIVES AND USES THEREOF | SCIFLUOR LIFE SCIENCES, INC. | 2019-02-07 | — | — | US | disclosed |
| US-9790222-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-10-17 | — | — | US | disclosed |