Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19788789 | 0.74 | PIK3CD (0.56) | PIK3CDAR | |
| SCHEMBL783215 | 0.74 | PIK3CD (0.64) | PIK3CDAR | |
| SCHEMBL26806204 | 0.73 | PIK3CD (0.42) | PIK3CD | |
| SCHEMBL21325017 | 0.72 | DPP4 (0.36) | DPP4 | |
| SCHEMBL24850757 | 0.72 | PIK3CD (0.50) | PIK3CD | |
| SCHEMBL20462574 | 0.71 | DPP4 (0.39) | DPP4 | |
| SCHEMBL24926254 | 0.71 | PIK3CD (0.49) | PIK3CD | |
| SCHEMBL13126749 | 0.71 | PIK3CD (0.57) | PIK3CD | |
| SCHEMBL25933093 | 0.71 | PIK3CD (0.35) | PIK3CD | |
| SCHEMBL24851104 | 0.70 | NAAA (0.49) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230029378-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230029378-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY | CBL, XIAP, BTK | PIK3CD 236/4885DPP4 3459/4885AR 3995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.